Basic Information
VIS ID
TVIS44004559
Fusion event
HTLV-1-LINC01483 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
67711250/69715109 (Hg38)
End
67711250/69715109 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01483
Nearest miRNA
hsa-mir-10226/Upstream/615453; hsa-mir-1250/Downstream/5033504;
Nearest TSS
ENST00000595228/Upstream/120243; ENST00000587241/Downstream/48568;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/387413, chr17-CpG: 87/Downstream/453663
Upstream sequence
AGACTCTGGCTGACCAGCAGACAAAAGAAAGGTATACACTCAGCTGAGGGCCAGTAGCAGACTCTACTTGAAGGATGATCTGGAGTGGAAGAAGAAATCG
Downstream sequence
GGCCACGATGAAGATGCCTTTTCCTTCACTGAGTAACTACCctttgctggtcacttcatacatactatctcattcatttctcgttactccaagaggtagc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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