Basic Information
VIS ID
TVIS44004564
Fusion event
HTLV-1-CERNA3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
56987591/56075032 (Hg38)
End
56987591/56075032 (Hg38)
Orient
-
Location type
Intronic
Target gene
CERNA3
Nearest miRNA
hsa-mir-124-1/Upstream/13178757; hsa-mir-10400/Downstream/5639756;
Nearest TSS
ENST00000518652/Upstream/440; ENST00000518169/Downstream/38950;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/283, chr8-CpG: 75/Downstream/37955
Nearby gene
RPS20(-451) ;
Upstream sequence
ATCTGGATAACTTACGTTAGAATTAGTAAGCAGTTATTTTTCATAGCCTGAAACGTCCTGTTGTGATATTTCAGCTCCTGGCTTCCCAGTCCAGCAGAAG
Downstream sequence
TATCTACATCTATTTCTGGAAAGGACCTGAACTTGGCTTCTCGTCCTTCTGGAAAGTGAGGCGAAAATGCCAGGCTGCGCAGCTATCCTGAGGCCCGGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate