Basic Information
VIS ID
TVIS44004566
Fusion event
HTLV-1-NAALADL2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
174669420/174951630 (Hg38)
End
174669420/174951630 (Hg38)
Orient
+
Location type
Intronic
Target gene
NAALADL2
Nearest miRNA
hsa-let-7g/Upstream/3844871; hsa-mir-1224/Downstream/417910;
Nearest TSS
ENST00000440867/Upstream/87814; ENST00000414826/Downstream/172776;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/510072, chr3-CpG: 133/Downstream/2244819
Upstream sequence
CTCTAAATCTTTTTAATTTTAATTGATAGTAGATGGTGAGGCAATATATGTTTAGGTAAAGTTAATATAAAGAGTTCAGGTAATAAAACAAAAGTTGTGC
Downstream sequence
CTAAGTGCTTTTATATTCTTTTTACTTGTCGATAGACGCCTTCAACTTTAAATGTTGTAATCAATATAACTTTGTGTTGCATCATCCTTCCTGCAATATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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