Basic Information
VIS ID
TVIS44004567
Fusion event
HTLV-1-HSD11B1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
209856209/209682864 (Hg38)
End
209856209/209682864 (Hg38)
Orient
-
Location type
Intronic
Target gene
HSD11B1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/59354; hsa-mir-1182/Downstream/2394749;
Nearest TSS
ENST00000473358/Upstream/7444; ENST00000615289/Downstream/3314;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6781, chr1-CpG: 28/Downstream/64744
Nearby gene
HSD11B1(+3316) ;
Upstream sequence
TAACTGCATCTCAGAGTGCTAACCAATCAACAAATAGTCATGCTTCTATAGCTGATGTTAGCCCATTTATGTCTGGGAAAGTACACCAGTCCCTGACCTT
Downstream sequence
CATGCATCCTCGAAACCCTATATGAGATCAGCAGCCTGCTTTTCAGAGAGATTGAGCAGCAAAGCTTGCCCTTACTATAATGAGCAATAAGTTTACCATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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