Basic Information
VIS ID
TVIS44004583
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114806257/114048680 (Hg38)
End
114806257/114048680 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2B
Nearest miRNA
hsa-mir-1285-2/Upstream/327312; hsa-mir-10b/Downstream/13374857;
Nearest TSS
ENST00000437798/Upstream/68771; ENST00000492708/Downstream/74613;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/68568, chr2-CpG: 51/Downstream/613471
Nearby gene
LINC01191(No orient, 41370)
Upstream sequence
AGGCAAGAGCAATCTGGCTCTaggggtctcccttttggcaaggatcatacactattgaccatggggtctgtttaacaaggagattggactggtcaccacc
Downstream sequence
ttctttTATGTCTCTTTGATCCTCCCTTGGGTCACTCCTTCCCCCCAACACATCATGtattttatgtctagtactgttttgagtgcgttccatagatcaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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