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TVIS44004603
Basic Information
VIS ID
TVIS44004603
Fusion event
HTLV-1-PGBD4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
34394377/34102176 (Hg38)
End
34394377/34102176 (Hg38)
Orient
+
Location type
UTR5
Target gene
PGBD4
miRNAs that regulate target gene
hsa-mir-297
;
hsa-mir-3978
;
hsa-mir-3924
;
hsa-mir-567
;
hsa-mir-5093
;
hsa-mir-380-3p
;
hsa-mir-411-3p
;
hsa-mir-379-3p
;
hsa-mir-4495
;
hsa-mir-101-3p
;
hsa-mir-574-5p
;
hsa-mir-4455
;
hsa-mir-4762-3p
;
hsa-mir-4303
;
hsa-mir-6867-5p
;
hsa-mir-6513-3p
;
hsa-mir-595
;
hsa-mir-5096
;
hsa-mir-511-5p
;
hsa-mir-6740-3p
;
hsa-mir-501-5p
;
hsa-mir-577
;
hsa-mir-500a-5p
;
hsa-mir-619-5p
;
hsa-mir-5004-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-150-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-6814-5p
;
hsa-mir-5697
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-562
;
hsa-mir-4279
;
hsa-mir-6778-3p
;
hsa-mir-5571-5p
;
hsa-mir-5698
;
hsa-mir-3689d
;
hsa-mir-143-5p
;
hsa-mir-6879-3p
;
hsa-mir-3650
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-4695-3p
;
hsa-mir-4772-3p
;
hsa-mir-6787-3p
;
hsa-mir-4485-5p
;
hsa-mir-6736-3p
;
hsa-mir-6890-3p
;
hsa-mir-500b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-2681-3p
;
hsa-mir-30b-3p
;
hsa-mir-3192-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-4728-5p
;
hsa-mir-490-3p
;
hsa-mir-582-5p
;
hsa-mir-6134
;
hsa-mir-655-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6799-5p
;
hsa-mir-6807-5p
;
hsa-mir-6851-5p
;
hsa-mir-6880-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-7847-3p
;
hsa-mir-7851-3p
;
hsa-mir-96-3p
Nearest miRNA
hsa-mir-1268a/Upstream/3037035; hsa-mir-10393/Downstream/279893;
Nearest TSS
ENST00000557528/Upstream/103;
ENST00000557941/Downstream/43679;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/113
,
chr15-CpG: 83/Downstream/107324
Upstream sequence
TCAAGTGCCTATGAAGGGGACTGCCCATGAAGTGAAAGTCAAGTGTGTGTTGCTGCGGCAGCCACGGAGGCCAAGGACCTCACGGGAGTAAAAGATGACG
Downstream sequence
AGACTGGCTTCGGGAGAAACACCATCCAGAAGAGACCTTTCAAAAAACTTCTAGAGACTCCCCAAGACGTATGAGATGAAAGGCTTCTTCTGTCTGTGTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL111
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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