Basic Information
VIS ID
TVIS44004604
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
64153870/63861671 (Hg38)
End
64153870/63861671 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA15A
Nearest miRNA
hsa-mir-10393/Upstream/1037630; hsa-mir-11181/Downstream/9259;
Nearest TSS
ENST00000557528/Upstream/27729; ENST00000558050/Downstream/50272;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/27205, chr15-CpG: 72/Downstream/184282
Nearby gene
MIR422A(-9259) ;
Nearest cancer related gene
MIR422A(TSG, -9259) ;
Upstream sequence
agacggacaatgaacaaataacaaataaatctacagtatatcagactgtgataagagctacagagaaaatacaaagctgggtaaaggagtgaagagtgCC
Downstream sequence
CAGATAGACATTGCTGggatcgcttgaggtcaagagttcaagaccagcctgggcaacatggttaaacccagtctctactaaaaatacaaaaattaactgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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