VISDB Viral Integration Site DataBase

VIS ID

TVIS44004614

Fusion event

HTLV-1-HOOK3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

42787726/42932583 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-mir-181a-3p ; hsa-mir-181a-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-4662a-5p ; hsa-mir-6787-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-5692a ; hsa-mir-2681-5p ; hsa-mir-3529-3p ; hsa-mir-578 ; hsa-mir-3683 ; hsa-mir-1273c ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-3653-5p ; hsa-mir-6790-3p ; hsa-mir-6513-3p ; hsa-mir-1224-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-6844 ; hsa-mir-2052 ; hsa-mir-4508 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-4314 ; hsa-mir-7977 ; hsa-mir-6806-5p ; hsa-mir-3178 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4486 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-514a-5p ; hsa-mir-665 ; hsa-mir-5089-5p ; hsa-let-7e-3p ; hsa-let-7d-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-2115-5p ; hsa-mir-4305 ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-5586-5p ; hsa-mir-1273e ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-219b-3p ; hsa-mir-17-3p ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-302f ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-27b-5p ; hsa-mir-556-5p ; hsa-mir-541-3p ; hsa-mir-1827 ; hsa-mir-25-5p ; hsa-mir-3664-3p ; hsa-mir-4327 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6087 ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-940 ; hsa-mir-4537 ; hsa-mir-510-3p ; hsa-mir-5585-5p ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-134-3p ; hsa-mir-143-3p ; hsa-mir-3136-3p ; hsa-mir-3198 ; hsa-mir-3664-5p ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-452-5p ; hsa-mir-4534 ; hsa-mir-4639-3p ; hsa-mir-4676-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-663b ; hsa-mir-6794-3p ; hsa-mir-7108-5p ; hsa-mir-7114-5p ; hsa-mir-7155-3p ; hsa-mir-8055 ; hsa-mir-8082 ; hsa-mir-892c-3p

Nearest miRNA

hsa-mir-124-1/Upstream/36308; hsa-mir-10400/Downstream/18782205;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/34594, chr8-CpG: 89/Downstream/123489

Upstream sequence

AGCCATTATCCTCGTCTCATACATGAGAAGCCAAGGCTCATATGCACCTCTTTCTCTTCCCTTCTTGTAATTTTTCTTTTTTTTCTCCCCCTCACCCAGC

Downstream sequence

CCCCTGACATTTTTGGGTCCTAGGCCTACTGGTGTTACCTGTAGCCCCACATAGCATCCCCTAGCCTGAGCGTGCCTGAGAGGAAGAAGAAATCCAGTCT