Basic Information
VIS ID
TVIS44004621
Fusion event
HTLV-1-LASP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
End
37057928/38901675 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-218-5p ; hsa-mir-133a-3p ; hsa-mir-193b-3p ; hsa-mir-505-5p ; hsa-mir-23b-3p ; hsa-mir-203a-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-625-5p ; hsa-mir-1910-3p ; hsa-mir-3136-3p ; hsa-mir-548t-5p ; hsa-mir-3153 ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-4666b ; hsa-mir-548az-5p ; hsa-mir-6511a-5p ; hsa-mir-6733-5p ; hsa-mir-6734-5p ; hsa-mir-6739-5p ; hsa-mir-6768-3p ; hsa-mir-6795-5p ; hsa-mir-6818-5p ; hsa-mir-6887-5p ; hsa-mir-7155-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-1294 ; hsa-mir-4316 ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-29b-3p ; hsa-mir-92a-3p ; hsa-mir-1-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1184 ; hsa-mir-1197 ; hsa-mir-125a-3p ; hsa-mir-1265 ; hsa-mir-1285-3p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-185-5p ; hsa-mir-2861 ; hsa-mir-3117-3p ; hsa-mir-3175 ; hsa-mir-3187-5p ; hsa-mir-3605-5p ; hsa-mir-3665 ; hsa-mir-3925-5p ; hsa-mir-4306 ; hsa-mir-4419a ; hsa-mir-4459 ; hsa-mir-4510 ; hsa-mir-4512 ; hsa-mir-451b ; hsa-mir-4644 ; hsa-mir-4688 ; hsa-mir-4710 ; hsa-mir-4722-5p ; hsa-mir-4728-5p ; hsa-mir-4736 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4764-5p ; hsa-mir-4773 ; hsa-mir-486-3p ; hsa-mir-5008-5p ; hsa-mir-5189-5p ; hsa-mir-6077 ; hsa-mir-6089 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-612 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6721-5p ; hsa-mir-6731-5p ; hsa-mir-6743-5p ; hsa-mir-6774-5p ; hsa-mir-6785-5p ; hsa-mir-6860 ; hsa-mir-6873-5p ; hsa-mir-6883-5p ; hsa-mir-6894-5p ; hsa-mir-8085 ; hsa-mir-936
Nearest miRNA
hsa-mir-1180/Upstream/75783; hsa-mir-10226/Downstream/13304;
Upstream sequence
ccctggctgccagaatcagcgtctctgggagtggggcccaggaatcagcatgttagacacattccctgggtttctgtggtgctctctgaagtttgagagc
Downstream sequence
cacCACCTAAAAGTCTGAAAAAGCTTCACCAACCCCTAAGTCAGAGGGTGCCAGATCAGGCTGTACCTCAGAACCCCAGGGGAGCtttatttttattttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate