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TVIS44004621
Basic Information
VIS ID
TVIS44004621
Fusion event
HTLV-1-LASP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
37057928/38901675 (Hg38)
End
37057928/38901675 (Hg38)
Orient
-
Location type
Intronic
Target gene
LASP1
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-218-5p
;
hsa-mir-133a-3p
;
hsa-mir-193b-3p
;
hsa-mir-505-5p
;
hsa-mir-23b-3p
;
hsa-mir-203a-3p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-625-5p
;
hsa-mir-1910-3p
;
hsa-mir-3136-3p
;
hsa-mir-548t-5p
;
hsa-mir-3153
;
hsa-mir-3714
;
hsa-mir-548an
;
hsa-mir-4666b
;
hsa-mir-548az-5p
;
hsa-mir-6511a-5p
;
hsa-mir-6733-5p
;
hsa-mir-6734-5p
;
hsa-mir-6739-5p
;
hsa-mir-6768-3p
;
hsa-mir-6795-5p
;
hsa-mir-6818-5p
;
hsa-mir-6887-5p
;
hsa-mir-7155-3p
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-1294
;
hsa-mir-4316
;
hsa-mir-6738-5p
;
hsa-mir-5194
;
hsa-mir-1914-3p
;
hsa-mir-29b-3p
;
hsa-mir-92a-3p
;
hsa-mir-1-5p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-1184
;
hsa-mir-1197
;
hsa-mir-125a-3p
;
hsa-mir-1265
;
hsa-mir-1285-3p
;
hsa-mir-1321
;
hsa-mir-149-3p
;
hsa-mir-185-5p
;
hsa-mir-2861
;
hsa-mir-3117-3p
;
hsa-mir-3175
;
hsa-mir-3187-5p
;
hsa-mir-3605-5p
;
hsa-mir-3665
;
hsa-mir-3925-5p
;
hsa-mir-4306
;
hsa-mir-4419a
;
hsa-mir-4459
;
hsa-mir-4510
;
hsa-mir-4512
;
hsa-mir-451b
;
hsa-mir-4644
;
hsa-mir-4688
;
hsa-mir-4710
;
hsa-mir-4722-5p
;
hsa-mir-4728-5p
;
hsa-mir-4736
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-4764-5p
;
hsa-mir-4773
;
hsa-mir-486-3p
;
hsa-mir-5008-5p
;
hsa-mir-5189-5p
;
hsa-mir-6077
;
hsa-mir-6089
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-612
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6721-5p
;
hsa-mir-6731-5p
;
hsa-mir-6743-5p
;
hsa-mir-6774-5p
;
hsa-mir-6785-5p
;
hsa-mir-6860
;
hsa-mir-6873-5p
;
hsa-mir-6883-5p
;
hsa-mir-6894-5p
;
hsa-mir-8085
;
hsa-mir-936
Nearest miRNA
hsa-mir-1180/Upstream/75783; hsa-mir-10226/Downstream/13304;
Nearest TSS
ENST00000595228/Upstream/11441;
ENST00000579123/Downstream/2925;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/30824
,
chr17-CpG: 30/Downstream/16932
Upstream sequence
ccctggctgccagaatcagcgtctctgggagtggggcccaggaatcagcatgttagacacattccctgggtttctgtggtgctctctgaagtttgagagc
Downstream sequence
cacCACCTAAAAGTCTGAAAAAGCTTCACCAACCCCTAAGTCAGAGGGTGCCAGATCAGGCTGTACCTCAGAACCCCAGGGGAGCtttatttttattttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL48
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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