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TVIS44004666
Basic Information
VIS ID
TVIS44004666
Fusion event
HTLV-1-LSM3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
14238162/14196662 (Hg38)
End
14238162/14196662 (Hg38)
Orient
-
Location type
Intronic
Target gene
LSM3
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-26b-5p
;
hsa-mir-128-3p
;
hsa-mir-196a-5p
;
hsa-mir-944
;
hsa-mir-3190-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6763-3p
;
hsa-mir-4433b-3p
;
hsa-mir-1231
;
hsa-mir-6807-5p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-7155-3p
;
hsa-mir-3136-3p
;
hsa-mir-3922-3p
;
hsa-mir-3176
;
hsa-mir-3190-5p
;
hsa-mir-6504-3p
;
hsa-mir-654-3p
;
hsa-mir-4438
;
hsa-mir-6077
;
hsa-mir-7-5p
;
hsa-mir-5587-3p
;
hsa-mir-4707-5p
;
hsa-mir-4731-5p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-6809-3p
;
hsa-mir-4768-5p
;
hsa-mir-6833-3p
;
hsa-mir-675-3p
;
hsa-mir-889-3p
;
hsa-mir-657
;
hsa-mir-3665
;
hsa-mir-4698
;
hsa-mir-8063
Nearest miRNA
hsa-mir-12127/Upstream/3802100; hsa-let-7g/Downstream/1299577;
Nearest TSS
ENST00000440867/Upstream/17879;
ENST00000622810/Downstream/107183;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/17754
,
chr3-CpG: 39/Downstream/101087
Upstream sequence
acagttactggtccctaacagtggtgaatcccactgggaaggcatgaatgctccctgtcctggtagcagcagaaatccctcaattagatcAAATATGTCC
Downstream sequence
CATCCAATGTTTGGAACTTATACTaaatttaattgtgcgtcctacatctttatttgcaaaatctggcaaccctaAATGGGGTCCGCAGAGCTTTCAGGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL12
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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