VISDB Viral Integration Site DataBase

VIS ID

TVIS44004690

Fusion event

HTLV-1-TMEM120B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

122151766/121713860 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-766-3p ; hsa-mir-331-3p ; hsa-mir-30c-5p ; hsa-mir-4326 ; hsa-mir-1273g-3p ; hsa-mir-6516-5p ; hsa-mir-592 ; hsa-mir-455-3p ; hsa-mir-7703 ; hsa-mir-597-5p ; hsa-mir-668-3p ; hsa-mir-6499-3p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-5186 ; hsa-mir-4793-3p ; hsa-mir-6890-3p ; hsa-mir-508-5p ; hsa-mir-3149 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-4735-5p ; hsa-mir-590-3p ; hsa-mir-2053 ; hsa-mir-6879-3p ; hsa-mir-4524a-3p ; hsa-mir-6773-3p ; hsa-mir-215-3p ; hsa-mir-6812-3p ; hsa-mir-500b-3p ; hsa-mir-4524b-3p ; hsa-mir-1182 ; hsa-mir-6895-5p ; hsa-mir-4755-3p ; hsa-mir-342-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-5693 ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-1228-3p ; hsa-mir-5582-5p ; hsa-mir-34a-3p ; hsa-mir-7977 ; hsa-mir-4738-5p ; hsa-mir-4674 ; hsa-mir-4437 ; hsa-mir-6778-3p ; hsa-mir-378g ; hsa-mir-6850-3p ; hsa-mir-4740-3p ; hsa-mir-22-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4767 ; hsa-mir-6087 ; hsa-mir-6089 ; hsa-mir-383-3p ; hsa-mir-129-5p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-4314 ; hsa-mir-6716-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4797-5p ; hsa-mir-194-5p ; hsa-mir-555 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-6861-5p ; hsa-mir-143-5p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-4743-3p ; hsa-mir-4778-5p ; hsa-mir-484 ; hsa-mir-510-5p ; hsa-mir-5586-3p ; hsa-mir-6758-3p ; hsa-mir-6888-3p

Nearest miRNA

hsa-let-7i/Upstream/269508; hsa-mir-3612/Downstream/982047;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/675, chr12-CpG: 132/Downstream/79137

Upstream sequence

GAGACGCCTCAGGAAACCTTGGGGTTGACCAAGAGGGACTCGGTGACTATTTTTGAAGACAGGGCTGTTCCCTCTCCAGTCACGGGATTGTTTTTCGGGG

Downstream sequence

GGTTGGCTTTGCCTGAAATTACATTGCACACTATCACCCCAGTCCTCTCATTTGGAGCAGTGACATTGTCCCTGTCCATGTACCTCTTGTCTGCAGTTCA