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Viral Integration Site DataBase
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TVIS44004719
Basic Information
VIS ID
TVIS44004719
Fusion event
HTLV-1-ZNF704 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
81612658/80700423 (Hg38)
End
81612658/80700423 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF704
miRNAs that regulate target gene
hsa-mir-192-5p
;
hsa-mir-744-5p
;
hsa-mir-511-5p
;
hsa-mir-23c
;
hsa-mir-23b-3p
;
hsa-mir-23a-3p
;
hsa-mir-130a-5p
;
hsa-mir-431-5p
;
hsa-mir-4635
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-203a-3p
;
hsa-mir-4423-3p
;
hsa-mir-6069
;
hsa-mir-4745-3p
;
hsa-mir-1538
;
hsa-mir-3934-3p
;
hsa-mir-484
;
hsa-mir-3155b
;
hsa-mir-3155a
;
hsa-mir-3622a-5p
;
hsa-mir-5582-5p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-152-5p
;
hsa-mir-597-3p
;
hsa-mir-182-3p
;
hsa-mir-4267
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3663-5p
;
hsa-mir-6513-3p
;
hsa-mir-888-3p
;
hsa-mir-606
;
hsa-mir-6826-3p
;
hsa-mir-6892-3p
;
hsa-mir-6795-3p
;
hsa-mir-6887-3p
;
hsa-mir-135a-3p
;
hsa-mir-3158-3p
;
hsa-mir-4446-3p
;
hsa-mir-5088-5p
;
hsa-mir-643
;
hsa-mir-4446-5p
;
hsa-mir-3679-3p
;
hsa-mir-675-3p
;
hsa-mir-2355-5p
;
hsa-mir-4524b-5p
;
hsa-mir-4524a-5p
;
hsa-mir-621
;
hsa-mir-1468-3p
;
hsa-mir-6793-3p
;
hsa-mir-545-3p
;
hsa-mir-3146
;
hsa-mir-646
;
hsa-mir-503-5p
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-548p
;
hsa-let-7a-2-3p
;
hsa-let-7g-3p
;
hsa-mir-130b-5p
;
hsa-mir-133a-3p
;
hsa-mir-133b
;
hsa-mir-3120-5p
;
hsa-mir-3177-5p
;
hsa-mir-4421
;
hsa-mir-4527
;
hsa-mir-4753-3p
;
hsa-mir-5699-3p
;
hsa-mir-6503-5p
;
hsa-mir-6753-3p
;
hsa-mir-6809-3p
;
hsa-mir-6843-3p
;
hsa-mir-6848-3p
;
hsa-mir-7107-3p
;
hsa-mir-942-5p
;
hsa-mir-9-5p
Nearest miRNA
hsa-mir-12123/Upstream/458950; hsa-mir-10400/Downstream/10505062;
Nearest TSS
ENST00000518652/Upstream/27084;
ENST00000518302/Downstream/113836;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/121322
,
chr8-CpG: 181/Downstream/172767
Upstream sequence
acagactgcagtttaatccccaaaacctccatttattagtgagtgcttttaggcaaatcttgcagcttcacaaaacttcagattcctcatctgtaaaatg
Downstream sequence
gaaatgacaataatacagaccttagagggtttggaagagttaaataagatgtgtaaaatatctggcatatactaaacactcaaGTTATTATTATCCTCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL85
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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