Basic Information
VIS ID
TVIS44004724
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
120482285/119470045 (Hg38)
End
120482285/119470045 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/144780; hsa-mir-10400/Downstream/3745743;
Nearest TSS
ENST00000518652/Upstream/7695; ENST00000518057/Downstream/108440;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/53107, chr8-CpG: 29/Downstream/362513
Nearby gene
CCN3(+45607) ;
Nearest cancer related gene
CCN3(OG, +45607) ;
Upstream sequence
tgtacccctgaacttaaaacaaaagttaaaaatacagatagatagatagatagatgatagatagatagatagatagatagatagatagatagataggtag
Downstream sequence
atagatagatagaagcttaaaatctgtgagatatagctaaagcttttcttaaaggtaatgtacagtatgaaatgcttctattagaaaagTTGTATGGCAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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