Basic Information
VIS ID
TVIS44004732
Fusion event
HTLV-1-LINC01527 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
152917716/152945240 (Hg38)
End
152917716/152945240 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
LINC01527
Nearest miRNA
hsa-mir-101-1/Upstream/1399349; hsa-mir-1182/Downstream/744465;
Nearest TSS
ENST00000473358/Upstream/36695; ENST00000636302/Downstream/1914;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/429446, chr1-CpG: 111/Downstream/315756
Nearby gene
SPRR4(+25413) ;
Upstream sequence
GGACAGACTTGCCAAGCCAGGCTTCCCTCTGTCCTGTTGCCTTGGAAACAGCAAGGGCCTGGCCATCCTTGCTTCCCCCTGCATCCCCAGCATGGACATA
Downstream sequence
GTGCCTGGCACATGGAACAATTGCATCTTAATGAATAAATGGTTAGCCCAGGATAACAACTCCACATAGTCTTTCTTCTCTGCTATTAGGGACCTGAGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate