Basic Information
VIS ID
TVIS44004735
Fusion event
HTLV-1-LOC100049716 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
741339/632173 (Hg38)
End
741339/632173 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC100049716
Nearest miRNA
hsa-let-7i/Downstream/1028142;
Nearest TSS
ENST00000382841/Upstream/1282; ENST00000318291/Downstream/10501;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/22834, chr12-CpG: 102/Downstream/10413
Upstream sequence
GGTGGACTATTAGCAGGGAGTTGACTGGAGAATTAATCAGACGTTGAAGGGACATGGGGGACCCGGGAGGATGAAGTCTGAACTCGGGCTCAGGATATGG
Downstream sequence
AAAAAGATTGAGTAAAGCTGAGATTCCTGTGTGCTTAAAGTCCTAACCAGCCCCAGGGTGTCTGAGGCACGCTGGTAAGTAGAATCAGAGATTCCATTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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