Basic Information
VIS ID
TVIS44004738
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
53589895/52723728 (Hg38)
End
53589895/52723728 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/10981; hsa-mir-1243/Downstream/8198891;
Nearest TSS
ENST00000502981/Upstream/43119; ENST00000514957/Downstream/27671;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1160, chr4-CpG: 54/Downstream/27223
Nearby gene
DANCR(No orient, 9590)
Upstream sequence
gacagagctatactacattaaaaaaaagaaaaaaagaaatagaaagaaaGAGAGAGAGAAAGggaaggaagaaagggagggaaggaaggaaggaagggag
Downstream sequence
ggagggagggagggacggagggaggggaaagaaacgaagagaaagaaaggaaagaaaagaagggaaagaaaggaaagaaagaaagaaacagtacaccaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate