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TVIS44004753
Basic Information
VIS ID
TVIS44004753
Fusion event
HTLV-1-C17orf80 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
71233251/73237112 (Hg38)
End
71233251/73237112 (Hg38)
Orient
-
Location type
Intronic
Target gene
C17orf80
miRNAs that regulate target gene
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-155-5p
;
hsa-mir-125a-5p
;
hsa-mir-125b-5p
;
hsa-mir-3658
;
hsa-mir-580-3p
;
hsa-mir-6864-5p
;
hsa-mir-6126
;
hsa-mir-526b-5p
;
hsa-mir-3653-3p
;
hsa-mir-539-5p
;
hsa-mir-1252-5p
;
hsa-mir-4635
;
hsa-mir-8083
;
hsa-mir-5197-3p
Nearest miRNA
hsa-mir-10226/Upstream/4137456; hsa-mir-1250/Downstream/1511501;
Nearest TSS
ENST00000595228/Upstream/359;
ENST00000583547/Downstream/24768;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/4177
,
chr17-CpG: 55/Downstream/48614
Upstream sequence
CAATTGCCATCTGTCCCATCCAAAATGCTCTCTCTGCCTTTTGAATTTATAAGGGTCAAAATACTAACATTTTCAGTCATTTAGTTTATTTTCACCTAGG
Downstream sequence
CATGCCAGTAGACTGCATATAAAGTTGTCCTGAAAGAggctgggtgtagtggctcacacctgtaatctaagcactttgggaggctgaggccaaggcaggt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL127
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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