Basic Information
VIS ID
TVIS44004821
Fusion event
HTLV-1-ELF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
41622099/41047963 (Hg38)
End
41622099/41047963 (Hg38)
Orient
-
Location type
Intronic
Target gene
ELF1
miRNAs that regulate target gene
hsa-mir-194-5p
Nearest miRNA
hsa-mir-2276/Upstream/237102; hsa-mir-1267/Downstream/53056;
Nearest TSS
ENST00000623511/Upstream/28649; ENST00000379487/Downstream/13311;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/125293, chr13-CpG: 160/Downstream/12073
Nearby gene
WBP4(+13598) ;
Upstream sequence
ctgcccccagaggtggagtctacagaggcaggcaggcctccttgagctgcaatgggctccacccagttcgagcttcaggccactttgtttacctactcaa
Downstream sequence
gcctcagcaatggcgggtgccccttccccagcctcactgccaccttgcagttcgatctcagactgctgtgttagcaatgagcgagggtctgtgggcatga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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