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Viral Integration Site DataBase
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TVIS44004834
Basic Information
VIS ID
TVIS44004834
Fusion event
HTLV-1-RNF152 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
59515606/61848373 (Hg38)
End
59515606/61848373 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNF152
miRNAs that regulate target gene
hsa-mir-652-3p
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-526b-5p
;
hsa-mir-4680-5p
;
hsa-mir-4635
;
hsa-mir-548g-3p
;
hsa-mir-548av-3p
;
hsa-mir-513a-5p
;
hsa-mir-4305
;
hsa-mir-3681-3p
;
hsa-mir-1288-5p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-5694
;
hsa-mir-101-3p
;
hsa-mir-5683
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-514a-3p
;
hsa-mir-574-5p
;
hsa-mir-1238-3p
;
hsa-mir-670-3p
;
hsa-mir-6867-5p
;
hsa-mir-3650
;
hsa-mir-223-5p
;
hsa-mir-134-3p
;
hsa-mir-7114-5p
;
hsa-mir-6873-3p
;
hsa-mir-377-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-342-3p
;
hsa-mir-4789-3p
;
hsa-mir-8485
;
hsa-mir-4801
;
hsa-mir-4731-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-5009-3p
;
hsa-mir-5692a
;
hsa-mir-7851-3p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-4314
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6878-5p
;
hsa-mir-5186
;
hsa-mir-873-3p
;
hsa-mir-6857-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-3192-5p
;
hsa-mir-4646-5p
;
hsa-mir-204-3p
;
hsa-mir-3126-3p
;
hsa-mir-4499
Nearest miRNA
hsa-mir-1-2/Upstream/3397215; hsa-mir-5011/Downstream/5233211;
Nearest TSS
ENST00000575820/Upstream/99541;
ENST00000590713/Downstream/40481;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/293620
,
chr18-CpG: 129/Downstream/45103
Upstream sequence
GCTAAAGTTTTCTAGCTTTCTCAATATTTTTGCAAGATATCAGTGCTTCCACAATTTTTCTAACCATTAGTAATTATGCCACATTTTTTGAATGATTCCA
Downstream sequence
TAGCCTCAAAGAGAAGCTCTAGGTTTATATGTCAAATATAATCAAAGAAAAAAAAATCAATACCACCCTGCTACCATCACCTTCCCCCAGATAAAACCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL219
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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