Basic Information
VIS ID
TVIS44004835
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72255771/74588535 (Hg38)
End
72255771/74588535 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/1735153;
Nearest TSS
ENST00000575820/Upstream/12255; ENST00000309902/Downstream/9034;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/91731, chr18-CpG: 136/Downstream/8746
Nearby gene
LINC00909(No orient, 3239)
Upstream sequence
agtaggctatgccatctaggcttgtgtgggtacactctagggtggctgaagatgtccagacacgcatttctcagtatccctgttaagtgatgcatgattg
Downstream sequence
tatttctacaatttgaaaactgccagctctcctgctagactgtaacatctttacaggcagagattgtctgttttgtctatcctgatgtcttgaaggttcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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