Basic Information
VIS ID
TVIS44004873
Fusion event
HTLV-1-DDX11-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
31194248/31041314 (Hg38)
End
31194248/31041314 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
DDX11-AS1
Nearest miRNA
hsa-mir-1244-3/Upstream/5167235; hsa-let-7i/Downstream/11282386;
Nearest TSS
ENST00000382841/Upstream/114356; ENST00000535317/Downstream/19436;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/114370, chr12-CpG: 67/Downstream/32095
Upstream sequence
gatattatgtgactgtgggtcttccaagagtgtcctggtaattttagcaggcaattgacctatttaccttcaggctgccaatcctgtcagccgtccgcgg
Downstream sequence
gttgtgattccaatgccagttcttggttcgaagcctctgctattgtgcatttgggccaccagccagcctgggacctggatagtagtccatcctgtagttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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