Basic Information
VIS ID
TVIS44004884
Fusion event
HTLV-1-RSU1P2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
45607763/45112315 (Hg38)
End
45607763/45112315 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA10G
Target gene
RSU1P2
Nearest miRNA
hsa-mir-1265/Upstream/2114634; hsa-mir-107/Downstream/51699;
Nearest TSS
ENST00000439456/Upstream/111427; ENST00000483623/Downstream/69112;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/110977, chr10-CpG: 64/Downstream/86228
Upstream sequence
ATTAAACTTTAATAAAAGTTGACAGATATTGAAAGGTGGAAGGGACTGTGACAATAAAAATCATTCTAGTCATCGATGCTTCTCATAACAGATCCAGCTC
Downstream sequence
GGTCCAGTCCTACCAAGTGGGCCTCACCAGAAACAGCAGACAGCAGGGGGAAACCAAAATGGAAACGTGGGTTCCCCCTCTCAGGCAGAAAACGACCCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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