Basic Information
VIS ID
TVIS44004896
Fusion event
HTLV-1-ST8SIA6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.33
Reference genome
GRCh37/hg19
Start
17495717/17453718 (Hg38)
End
17495717/17453718 (Hg38)
Orient
+
Location type
Intronic
Target gene
ST8SIA6
Nearest miRNA
hsa-mir-1265/Upstream/3017057; hsa-mir-107/Downstream/391389;
Nearest TSS
ENST00000439456/Upstream/45691; ENST00000486183/Downstream/612;
Nearest CpG islands
chr10-CpG: 103/Target, None/Upstream, None/Downstream
Upstream sequence
GTGCCGTGGGTGGCCTCCCTGCTTTCCTCCACCAGAATCCTGCACAGCCGGGGAGAAAACTTAAGTTGCTACACCCCGCCGGGAGCTGTTGGCTGAAAGG
Downstream sequence
CTGGGAGTCGCGCTCCTTGCCTGGCAGGGAGATCTCGCACTCCCCGGCTCCCAGGCCAGGTCCCCAGCCCCAGAGTTGGAAGAGCCTTAGGGCGGGAAGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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