Basic Information
VIS ID
TVIS44004929
Fusion event
HTLV-1-LINC00299 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
8400457/8260327 (Hg38)
End
8400457/8260327 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00299
Nearest miRNA
hsa-mir-7158/Upstream/1609888; hsa-mir-10b/Downstream/1932287;
Nearest TSS
ENST00000437798/Upstream/120925; ENST00000331129/Downstream/17757;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/232171, chr2-CpG: 56/Downstream/196450
Upstream sequence
AATGTGGAAAGGCCCAGTCCTAGAGCACATTGATGATTAATTCCATCAGAAAGAAATGAAGCTTGCCGTAAAGTCATATGCTGGGATGTAGGTGGTGTCC
Downstream sequence
TAGAACGGGGAGTCCTAGGCAAATGAAGCAGCTGAGCGTCATGCGTTCGCAGCTAAGATAACCACATGCCAGCTTCAGAAAGGTGCTAAGATTCTGTCTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate