Basic Information
VIS ID
TVIS44004985
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
103678226/103212670 (Hg38)
End
103678226/103212670 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/2931362; hsa-mir-11399/Downstream/4684553;
Nearest TSS
ENST00000473358/Upstream/103798; ENST00000414923/Downstream/202209;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1975481, chr1-CpG: 85/Downstream/312800
Nearby gene
COL11A1(-104174) ;
Upstream sequence
GTTGGAAAAAAAGTGAACAATAAATTAGAAGCGTTGATGTTTCTTTCCAACTCTGTAACTTACCTACTTAATTACAGCAACAAAAATAAATGTTGGTTAA
Downstream sequence
TTTTCAGAAAAGTTGATCAGTTGCTAGATAGTGCTGACCAGGAGGAATTAAGACTGGGAACTGGTCTAGGACAGATGGTTAGAACCATGTTAGCAGTATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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