Basic Information
VIS ID
TVIS44005012
Fusion event
HTLV-1-STXBP5-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
147232198/146911062 (Hg38)
End
147232198/146911062 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
STXBP5-AS1
Nearest miRNA
hsa-mir-10398/Upstream/6227179; hsa-mir-1202/Downstream/4191613;
Nearest TSS
ENST00000381078/Upstream/51881; ENST00000359838/Downstream/544;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/311953, chr6-CpG: 133/Downstream/292615
Upstream sequence
AGGGATCCTTTTTTTAAGTTGATTCTCAGGGATAGAGCACGTTACCTTCACCACAGTAAGTTCCTCACAGGTGTAGAGTCCCGTTTGAATAAAAACATGT
Downstream sequence
GTCTTCTCAGACAAAATGTGTGTCCTCCCTGTGGCTTGCACAGCAGGGTGCCATGTCCCTCTCTGCTTTTCCCTCTCCCCTGGAGGGTCATCTTTCTTAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate