Basic Information
VIS ID
TVIS44005028
Fusion event
HTLV-1-LOC105373719 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
161978857/161122346 (Hg38)
End
161978857/161122346 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373719
Nearest miRNA
hsa-mir-128-1/Upstream/714464; hsa-mir-10b/Downstream/7460597;
Nearest TSS
ENST00000437798/Upstream/628552; ENST00000477952/Downstream/14562;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/628486, chr2-CpG: 39/Downstream/38026
Nearby gene
TANK(+14609) ;
Upstream sequence
AGCACCACGGTGAAGAGAGAGACTTTCTGGATAAACTGAGTCTGGGGTTTGATGCCATTTTTGTCCCACCCTCTATTTGCCATCATTCAAAGAACATGGT
Downstream sequence
CTCTTGCCAATTAGGTTTCCTTTTCCTTTCCCCATTGTTATATCGCCGGATAGTGTGTGGCTTCAATCAGAACttccaaaatatttggattttatgaact
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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