Basic Information
VIS ID
TVIS44005061
Fusion event
HTLV-1-LOC105373358 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
719010/719010 (Hg38)
End
719010/719010 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373358
Nearest miRNA
hsa-mir-10b/Downstream/5255652;
Nearest TSS
ENST00000437798/Upstream/25775; ENST00000425850/Downstream/12185;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/41332, chr2-CpG: 118/Downstream/13026
Nearby gene
TMEM18(-41571) ;
Upstream sequence
gtgtatgtgtgtatgtgtgtgtgtttctccattgtagatatcaccaaacacttttccaaagtggttgcaccaatttCTATGTCCATGGGTGGTGCAAAGC
Downstream sequence
TGCTTATATATTTATGAGCTACGTGGACAACTCTTTTGTAACACACATGCACACAGACATCGCCTTGCTTTCTCACTCTCATATGTCTTTTCATAAATAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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