Basic Information
VIS ID
TVIS44005069
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
176788550/175923822 (Hg38)
End
176788550/175923822 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2G
Nearest miRNA
hsa-mir-128-1/Upstream/756113; hsa-mir-10b/Downstream/226481;
Nearest TSS
ENST00000437798/Upstream/18320; ENST00000392539/Downstream/14034;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/742046, chr2-CpG: 48/Downstream/78143
Nearby gene
LNPK(-70) ;
Upstream sequence
CAAACTGATAAAGGGCAATTGGGGCAAGATACCTACTACCCAATAAATTTAGTAATTTTTAGTCATTTAAAATAGCATTAAAGTAGAAAATGTAGATTAG
Downstream sequence
TTTCTGAGGAGGAAAGAAATTAGGATGAGACAAATAATATATGGAGTGATAAAATTTAATAAGGTTTTCATTCTGTACTCAATTTTTATTCTTGTTTGTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate