Basic Information
VIS ID
TVIS44005073
Fusion event
HTLV-1-APOL5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36119541/35723494 (Hg38)
End
36119541/35723494 (Hg38)
Orient
+
Location type
Intronic
Target gene
APOL5
Nearest miRNA
hsa-mir-1286/Upstream/386695; hsa-let-7a-3/Downstream/563353;
Nearest TSS
ENST00000624155/Upstream/5622; ENST00000625157/Downstream/25138;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/171545, chr22-CpG: 131/Downstream/304677
Upstream sequence
ATAAGAAAATGGTACTTAAGAAcagtgattctcaaaggtcttgcagaactctgaagttccagatactgagccaaaatgattcaacaggaaaattgaatgg
Downstream sequence
tgattcttttttcgaactacaggaaaagtttgagtggagaggattttcccagttgtgccttttttcccttttcctcactttttcttaagatttacaagct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate