Basic Information
VIS ID
TVIS44005076
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
135428339/135709497 (Hg38)
End
135428339/135709497 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1271591; hsa-mir-1224/Downstream/15856379;
Nearest TSS
ENST00000440867/Upstream/576705; ENST00000447251/Downstream/256176;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/912359, chr3-CpG: 47/Downstream/256567
Nearby gene
PPP2R3A(+256176) ;
Upstream sequence
AAAAAATAGAAGAAGCAAGCTGTCAAAAGTCCAGGACATTGACACTCAATCCCCACATGAGTGTCTAGACCTGATCCACCATTGAATCCCCACAGCAGCC
Downstream sequence
CTCTCAGGGACTTGTACAGATTAAACACTTCAACAAGTATGCTTTTACTGGTTAGATGGATGGTTGGATGAATGGTTATCAAATAAAACTTTAACAAGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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