Basic Information
VIS ID
TVIS44005115
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
200599307/200630179 (Hg38)
End
200599307/200630179 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1771026; hsa-mir-1182/Downstream/1089329;
Nearest TSS
ENST00000473358/Upstream/9445; ENST00000568695/Downstream/18970;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9183, chr1-CpG: 74/Downstream/39305
Nearby gene
KIF14(-9445) ;
Nearest cancer related gene
KIF14(OG, -9445) ;
Upstream sequence
GAGTGAAAAAGATCTGCAGTGGCAGCTGAGGGAAAACTGAAGAAAGGGCCCCTTGGGGTCAGCATCTCCCGTAGCTTGCGCACTTTGCCTTCCACTATCA
Downstream sequence
CCCTCCACCAAAAATAAACGGGAGCAGCTTGAAGAGCAACCCAATATGCTTCAACCTACTTCTGGGCTTCCCAGTGaaactttaagtcttttgagggcag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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