Basic Information
VIS ID
TVIS44005116
Fusion event
HTLV-1-MIR548F3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
219242268/219068926 (Hg38)
End
219242268/219068926 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
MIR548F3
Nearest miRNA
hsa-mir-101-1/Upstream/6991241; hsa-mir-1182/Downstream/1048927;
Nearest TSS
ENST00000473358/Upstream/152742; ENST00000496776/Downstream/104918;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/721762, chr1-CpG: 46/Downstream/104841
Upstream sequence
AATGCTATGCATCGTAAGTGTGGCATGGAAGTAATTTTGCAAACAAAGTCATGAATAGTGGATCTAATTTATGGTCAAAGAAAGGTTAAAGCTGCATCCT
Downstream sequence
AAGTAAACATATAAGGGAAATGTGGTTTGTCTTTATTGCTGCTCTTTCCTCCCTTCTCCTTGCCATTTTCTTTCCTTAACTCCTTTTTGCTCCACCTTAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate