Basic Information
VIS ID
TVIS44005117
Fusion event
HTLV-1-EIF4A2P3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
58010160/58242688 (Hg38)
End
58010160/58242688 (Hg38)
Orient
-
Location type
Intronic
Target gene
EIF4A2P3
Nearest miRNA
hsa-mir-129-2/Upstream/601402; hsa-let-7a-2/Downstream/1352389;
Nearest TSS
ENST00000527297/Upstream/13770; ENST00000316059/Downstream/25572;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/489407, chr11-CpG: 132/Downstream/335512
Nearby gene
OR10Q1(-13770) ;
Upstream sequence
GGCATTGTGGCAGAAAGCAACACAACCTGAATACTTCTATTTAATTTTTGGAAAATCTCATAGATTTCATCCTTAAACCCTCAGCTCAACATTTCATCTG
Downstream sequence
CATCATCCAAAACAAACATTTTGATCCACCTTGGAGAAAAATATCTTATGTTTAGCATATCAAACACTCTCCATGGTGTACTAGCAACAGTATGTGGTGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate