Basic Information
VIS ID
TVIS44005134
Fusion event
HTLV-1-LOC105373592 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
122905123/122147547 (Hg38)
End
122905123/122147547 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373592
Nearest miRNA
hsa-mir-1285-2/Upstream/8426179; hsa-mir-10b/Downstream/5275990;
Nearest TSS
ENST00000437798/Upstream/357055; ENST00000435441/Downstream/917774;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/391597, chr2-CpG: 79/Downstream/1877128
Nearby gene
TSN(+379695) ;
Upstream sequence
tggctgcatggacatcattggaaatattagcaagggttatttaggtagaataatgggcatcagatacagatcagagtggaccgtggagtgcatggggtat
Downstream sequence
gaaggcacgagtgaagacaactcttccttaagggttgactgtaaaggggacgagggagacgggggagtagctgaaactggactctggcgactcagatgct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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