Basic Information
VIS ID
TVIS44005137
Fusion event
HTLV-1-LINC00114 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
40141090/38769166 (Hg38)
End
40141090/38769166 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00114
Nearest miRNA
hsa-let-7c/Upstream/3048358; hsa-mir-3197/Downstream/677844;
Nearest TSS
ENST00000624081/Upstream/21706; ENST00000432278/Downstream/36141;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/107425, chr21-CpG: 151/Downstream/35912
Upstream sequence
GAACTTAGCCTCTTACGTGCTTAATCACCTAATAAGacacacacacactcgcacacaaatcacacacacacatacacacacacacacTTAAAATACTTAT
Downstream sequence
TTTGGATTCTTGTGAATAAAATCCAGCTCAAGTCTATGGGAAAAAAAAATCATGGCCAGAAAAGTCTTTCCATTTTCACTGGGTACCAGCCAATAAATCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate