Basic Information
VIS ID
TVIS44005141
Fusion event
HTLV-1-GXYLT2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
End
72909323/72860172 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-1303 ; hsa-mir-545-5p ; hsa-mir-203a-3p ; hsa-mir-33a-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-455-3p ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-92a-2-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6134 ; hsa-mir-4487 ; hsa-mir-3160-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-5006-5p ; hsa-mir-6721-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-765 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-4784 ; hsa-mir-4722-5p ; hsa-mir-3150b-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-4459 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4436b-3p ; hsa-mir-4632-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3925-5p ; hsa-mir-3714 ; hsa-mir-5586-3p ; hsa-mir-4693-3p ; hsa-mir-4311 ; hsa-mir-558 ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-2278 ; hsa-mir-3924 ; hsa-mir-297 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-4302 ; hsa-mir-511-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-548an ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-586 ; hsa-mir-101-5p ; hsa-mir-633 ; hsa-mir-1179 ; hsa-mir-577 ; hsa-mir-3121-3p ; hsa-mir-4279 ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1281 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-122-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-7977 ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-3607-3p ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-34b-3p ; hsa-mir-605-5p ; hsa-mir-1288-5p ; hsa-mir-1910-3p ; hsa-mir-383-3p ; hsa-mir-516b-5p ; hsa-mir-6511a-5p
Nearest miRNA
hsa-let-7g/Upstream/1318083; hsa-mir-12124/Downstream/2354304;
Nearby gene
SHQ1(-11725) ;
Upstream sequence
AGATCCTTCTTCTAATCTTCTTCTTTTGATTTGTGCTCCATTCTCTACCCTGCTTTTTGCATATCCTCTGCAAGTGTTCATTCATGCTTCCATTTACTTG
Downstream sequence
AACTTCTTTTCTCTGCGTTGACATTTTCTTTGTTTCACATCAGTTTTTTGATGaatttttttttttttttttttGCCTTACAGGTTTTGTTTATTTACAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate