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TVIS44005156
Basic Information
VIS ID
TVIS44005156
Fusion event
HTLV-1-NUS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
118008976/117687813 (Hg38)
End
118008976/117687813 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUS1
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-32-5p
;
hsa-mir-877-3p
;
hsa-mir-31-3p
;
hsa-mir-484
;
hsa-mir-197-3p
;
hsa-mir-29b-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-518a-5p
;
hsa-mir-527
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-27a-3p
;
hsa-mir-105-5p
;
hsa-mir-27b-3p
;
hsa-mir-144-3p
;
hsa-mir-369-3p
;
hsa-mir-374a-5p
;
hsa-mir-651-3p
;
hsa-mir-374b-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-7853-5p
;
hsa-mir-548t-5p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-548az-5p
;
hsa-mir-2115-3p
;
hsa-mir-490-3p
;
hsa-mir-552-5p
;
hsa-mir-580-3p
;
hsa-mir-1277-5p
;
hsa-mir-4490
;
hsa-mir-33a-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-3681-3p
;
hsa-mir-1283
;
hsa-mir-195-3p
;
hsa-mir-16-2-3p
;
hsa-mir-34b-3p
;
hsa-mir-6827-5p
;
hsa-mir-504-3p
;
hsa-mir-3682-3p
;
hsa-mir-4705
;
hsa-mir-205-3p
;
hsa-mir-649
;
hsa-mir-548n
;
hsa-mir-107
;
hsa-mir-641
;
hsa-mir-103a-3p
;
hsa-mir-3617-5p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-6794-3p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-4639-3p
;
hsa-mir-5697
;
hsa-mir-3680-5p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-8064
Nearest miRNA
hsa-mir-10398/Upstream/10903593; hsa-mir-1202/Downstream/1381234;
Nearest TSS
ENST00000381078/Upstream/12311;
ENST00000360388/Downstream/219713;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/11601
,
chr6-CpG: 166/Downstream/219066
Upstream sequence
ACTTCATTTGATTTCTGTTCAACAAGCATGGAAGCATAGGCTGGAATGTTAATGTTGGGCTGAGCAGTTCGTTCTTAATACACTAGGCATTTTAGGAAAC
Downstream sequence
ATTTAAGATACTGAAGTTGGAATGTGCCAGGATTGAATAAGCTGGTGGTGAAGCTAGCAGTACTTAATAGAAGGGGGCAGGAACACCCACAGAAGTTGCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL74
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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