Basic Information
VIS ID
TVIS44005170
Fusion event
HTLV-1-LINC02777 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.1
Reference genome
GRCh37/hg19
Start
59381751/58916079 (Hg38)
End
59381751/58916079 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
LINC02777
Nearest miRNA
hsa-mir-12136/Upstream/3690356; hsa-mir-101-1/Downstream/817148;
Nearest TSS
ENST00000473358/Upstream/12332; ENST00000424308/Downstream/17564;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11851, chr1-CpG: 39/Downstream/230656
Nearby gene
LINC01135(No orient, 16367)
Upstream sequence
cattataaaactgcagtgatcagaacaatgtagtattgatgcaatgatagacaaacagatcagtggaacagaatatagaatcaagaagtagatccataga
Downstream sequence
tatatgggcagctgatttttgacaaagatgcaaaggcaatttagtgttttcaacaaatggttctagaacaattggataatctctatgaaaaaatattgat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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