Basic Information
VIS ID
TVIS44005197
Fusion event
HTLV-1-LOC101927967 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
78041704/77814578 (Hg38)
End
78041704/77814578 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
LOC101927967
Nearest miRNA
hsa-mir-1285-2/Upstream/2723664; hsa-mir-10b/Downstream/1834716;
Nearest TSS
ENST00000437798/Upstream/142363; ENST00000443419/Downstream/101356;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2103565, chr2-CpG: 32/Downstream/1178488
Upstream sequence
ttgagtatatttaattgtttaaaatgtagattacagttttcttctgttttgtgattattttttcttattttaacttatttttcctgcttttctgcaatac
Downstream sequence
ttctctgcaggacttgactttggttttgttaatttttaatataatgaagtgttttagataattgctgacactcttctgtcagtctagcaaagtccatgta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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