Basic Information
VIS ID
TVIS44005207
Fusion event
HTLV-1-LOC105378204 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141466940/142087375 (Hg38)
End
141466940/142087375 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378204
Nearest miRNA
hsa-mir-10397/Upstream/1439449; hsa-mir-103a-1/Downstream/1592485;
Nearest TSS
ENST00000502646/Upstream/74334; ENST00000509436/Downstream/21130;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/74246, chr5-CpG: 82/Downstream/21344
Nearby gene
NDFIP1(+21384) ;
Upstream sequence
AACCAAGCTGCAGAACATATTGTAGAGTACGCTTCACCCTTTTCCCCCTTTTTGGTAACTTTTAGAAAAGAATATAAACATACATGTACTTTTTCTGGTA
Downstream sequence
GAACCCATGAAAAACTATTAATAATCAATAGCTGTTATCATTAGGAAGGAAGGAATAGAAGTTAGCACTTGTCGTGTTATGCTTTCATGTTTAAAATTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate