Basic Information
VIS ID
TVIS44005238
Fusion event
HTLV-1-LOC105370324 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
98314134/97661880 (Hg38)
End
98314134/97661880 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
LOC105370324
Nearest miRNA
hsa-mir-1297/Upstream/1234588; hsa-mir-1267/Downstream/546644;
Nearest TSS
ENST00000623511/Upstream/227409; ENST00000604129/Downstream/16083;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/227015, chr13-CpG: 133/Downstream/313925
Nearby gene
RAP2A(+193882) ;
Upstream sequence
CCATCTGCAACACCTCCAGAATAGGTGCCTCTGCCAccaagccttgcagagtgaggaggagttgacctgccaataaaggtgtggagggtgcttcaggcag
Downstream sequence
atttggagtcagacttgagttcaagcaccatgagcactaattctgtactatttagcaagttagtctatctgtgtcttggtctgcccctctgtaaagtggt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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