Basic Information
VIS ID
TVIS44005258
Fusion event
HTLV-1-LINC01991 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
187684121/187966333 (Hg38)
End
187684121/187966333 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC01991
Nearest miRNA
hsa-let-7g/Upstream/1179556; hsa-mir-28/Downstream/722448;
Nearest TSS
ENST00000440867/Upstream/20112; ENST00000449845/Downstream/634;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/221396, chr3-CpG: 27/Downstream/187357
Nearby gene
LPP-AS2(-184873) ;
Upstream sequence
TAGATGAGTAGATAAAGAACAGATCTTGCAGTTCAAAAATGTGTGGGTAGCCAAAGGGAAGTGGCCACGTATTCGGCTACATGCCCTGTCATGCTGATGT
Downstream sequence
AGATTGACTTCCAATACAGGCTAGAGAATTCTCTTTGTATGGATGGACTCAGTCTGAGTGACACATGGTCCATGTCTCTTTGACTCTGGCCATGTTCTGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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