Basic Information
VIS ID
TVIS44005267
Fusion event
HTLV-1-LINC00473 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
GRCh37/hg19
Start
166385348/165971860 (Hg38)
End
166385348/165971860 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00473
Nearest miRNA
hsa-mir-10398/Upstream/7207107; hsa-mir-1913/Downstream/537494;
Nearest TSS
ENST00000381078/Upstream/217671; ENST00000629776/Downstream/14636;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/31115, chr6-CpG: 85/Downstream/16178
Upstream sequence
CCAGACATTTCCAAAGATAACTTGGCATTAATTTTGAAAACTGGCATTTTGGCAGCCACAGAGCttttatttatttattttattatttttaCCTCTGTAC
Downstream sequence
CTATCAAATCTAGACTACCCAGATTTCACTCTTGAAGGGGAAAATAAAGAACTGTATGTACCCATGGCGTTGACTTGGGCTTAACTTTAAACCTGTTAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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