Basic Information
VIS ID
TVIS44005274
Fusion event
HTLV-1-TRAPPC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
End
13751612/13733493 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-6834-5p ; hsa-mir-340-5p ; hsa-mir-4693-5p ; hsa-mir-542-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-3120-5p ; hsa-mir-7162-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-5584-5p ; hsa-mir-651-3p ; hsa-mir-6507-5p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-4252 ; hsa-mir-3128 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-1227-3p ; hsa-mir-6889-3p ; hsa-mir-5003-5p ; hsa-mir-596 ; hsa-mir-665 ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-432-5p ; hsa-mir-6078 ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-890 ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-7977 ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-383-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-873-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-4797-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6807-5p ; hsa-mir-6840-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-377-5p ; hsa-mir-4459 ; hsa-mir-4728-5p ; hsa-mir-6086 ; hsa-mir-6087 ; hsa-mir-658 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p
Nearest miRNA
hsa-mir-3690-1/Upstream/143147; hsa-let-7f-2/Downstream/2893519;
Nearest CpG islands
Upstream sequence
TTCAGAGCTACTATCATttctctcttcatgcctggaatgttctcctttattctgtctgcaaccactacccatcctttaaaatccaactaagcctctcctc
Downstream sequence
cTTTTCCATTGTTTCCAACAAAAACTTACAGGTTCTCCACCTCCTATGAAGTCCTGTCACTCTTACTGCCTCTTAAATACTTTAAGTTTTTCACAGCCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate