Basic Information
VIS ID
TVIS44005317
Fusion event
HTLV-1-CLBA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
105464425/104998088 (Hg38)
End
105464425/104998088 (Hg38)
Orient
-
Location type
Intronic
Target gene
CLBA1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1185-1/Upstream/132677; hsa-mir-4507/Downstream/152690;
Nearest TSS
ENST00000550708/Upstream/6566; ENST00000548104/Downstream/22972;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/5758, chr14-CpG: 160/Downstream/22186
Upstream sequence
acagagtgagactctatctcaaaaaaataaagaaagaaagaaaagaaaaaaatattctttaaaaatgaaggCATTATCAGCCAGGATACAGAAACCACAC
Downstream sequence
CAGTTATCTGAAGAGGAAAAAATGTAAAGAATTACTAGGCCCGGTATgtggttcatacctgtaatcccagcactttgagaggccaaggtggaaggattgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate