Basic Information
VIS ID
TVIS44005320
Fusion event
HTLV-1-FEM1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
End
68572186/68279848 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-30b-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-578 ; hsa-mir-6715b-3p ; hsa-mir-3655 ; hsa-mir-3682-5p ; hsa-mir-138-1-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-1229-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-340-5p ; hsa-mir-4473 ; hsa-mir-4662a-5p ; hsa-mir-4711-3p ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-6499-3p ; hsa-mir-302a-5p ; hsa-mir-7152-3p ; hsa-mir-6861-5p ; hsa-mir-6758-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-6733-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-4519 ; hsa-mir-3121-3p ; hsa-mir-5692a ; hsa-mir-6792-5p ; hsa-mir-646 ; hsa-mir-5003-3p ; hsa-mir-374b-3p ; hsa-mir-5682 ; hsa-mir-585-5p ; hsa-mir-6871-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-29c-3p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-4477a ; hsa-mir-5087 ; hsa-mir-3913-3p ; hsa-mir-4307 ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-224-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-6507-3p ; hsa-mir-106b-5p ; hsa-mir-17-5p ; hsa-mir-106a-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-489-3p ; hsa-mir-6083 ; hsa-mir-4326 ; hsa-mir-26b-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-511-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-4291 ; hsa-mir-6740-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5088-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-10393/Upstream/1782814; hsa-mir-11181/Downstream/522002;
Upstream sequence
TAAAAGCTTTTTCTTCTATTTTAGATGAGTGGAAAATATTCATAGCATTACATCTTAATGAAATGGTAGCCCATGGGCAATGGCTTATATCACGGGTATC
Downstream sequence
ACCATTATACACATTAAGGAGATGTTTTTTTTCATGTTGACCAAAGATGGCAACCTGATTCATGTTTGCTTTTCCTTACTGGCTTTCGTGTCTTCTCTGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate