Basic Information
VIS ID
TVIS44005352
Fusion event
HTLV-1-LINC01446 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
53744745/53677052 (Hg38)
End
53744745/53677052 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01446
Nearest miRNA
hsa-mir-1183/Upstream/8795252; hsa-mir-10399/Downstream/3278733;
Nearest TSS
ENST00000635602/Upstream/108803; ENST00000629899/Downstream/134879;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/457553, chr7-CpG: 48/Downstream/864989
Upstream sequence
agagggattgctggtcacatggcagttctagttttaatttatttagaaattttcatactgttttccataattgtttcaccaatctacatttccatgaaca
Downstream sequence
gtgtacaagggttctcttttctcgacacccttgccagcattttcatctttaatttttttTCTTAAATGGATGTTCCTTTTATATTCATTAAACTGTACAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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