Basic Information
VIS ID
TVIS44005356
Fusion event
HTLV-1-ADAM3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
39344307/39486788 (Hg38)
End
39344307/39486788 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
ADAM3A
Nearest miRNA
hsa-mir-124-1/Upstream/9529440; hsa-mir-10400/Downstream/1784260;
Nearest TSS
ENST00000518652/Upstream/215912; ENST00000520001/Downstream/97701;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/378884, chr8-CpG: 30/Downstream/35918
Upstream sequence
ATAAACCTAGCTACAGTCTCATCCCTACAGTGCCGTTCTGGTGCAGGAATGTGTATATGTACGAAGACAGCTGTGCTAGTTAAAAACAAGTGTTACAATC
Downstream sequence
TCCCATAAATAGAGAGTTTTAACTGTAACCCTAATGCCTATGACTTCCCTGTGTAACTGGAGTCTGTTAAGTATTTCACTGAAAGGTACCAGCCACAAGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate