Basic Information
VIS ID
TVIS44005366
Fusion event
HTLV-1-CSNK2A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
End
510723/530079 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-216b-5p ; hsa-mir-337-3p ; hsa-mir-760 ; hsa-mir-186-5p ; hsa-mir-22-3p ; hsa-mir-652-3p ; hsa-mir-615-3p ; hsa-mir-183-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-125b-5p ; hsa-mir-4799-5p ; hsa-mir-6765-5p ; hsa-mir-1304-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-3188 ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-5009-3p ; hsa-mir-485-5p ; hsa-mir-6884-5p ; hsa-mir-4662a-5p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-138-1-3p ; hsa-mir-4319 ; hsa-mir-125a-5p ; hsa-mir-625-3p ; hsa-mir-504-5p ; hsa-mir-580-3p ; hsa-mir-6867-3p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-7706 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-3162-3p ; hsa-mir-3163 ; hsa-mir-4695-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-518e-3p ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-6888-5p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-5581-3p ; hsa-mir-103a-2-5p ; hsa-mir-6499-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-136-5p ; hsa-mir-6872-3p ; hsa-mir-193a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6868-3p ; hsa-mir-6749-3p ; hsa-mir-3124-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-646 ; hsa-mir-1183 ; hsa-mir-1266-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-1825 ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-3671 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-4762-5p ; hsa-mir-607
Nearest miRNA
hsa-mir-1-1/Downstream/862821;
Nearest cancer related gene
CSNK2A1(OG, No orient, 0)
Upstream sequence
TAAAAattgagataaaatccatgtaacataaaactcatcattttagggtacaatcagtaccctaaaatggtgtgttttcgtatattcacaatgctgtgga
Downstream sequence
accatcaccactatctgattccagaacacttcatcgccccaaaaagaaacccagtacctcagaggattaactcccaatagcctcttcctacaatcctctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate