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TVIS44005366
Basic Information
VIS ID
TVIS44005366
Fusion event
HTLV-1-CSNK2A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
GRCh37/hg19
Start
510723/530079 (Hg38)
End
510723/530079 (Hg38)
Orient
+
Location type
Intronic
Target gene
CSNK2A1
miRNAs that regulate target gene
hsa-mir-216b-5p
;
hsa-mir-337-3p
;
hsa-mir-760
;
hsa-mir-186-5p
;
hsa-mir-22-3p
;
hsa-mir-652-3p
;
hsa-mir-615-3p
;
hsa-mir-183-5p
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-125b-5p
;
hsa-mir-4799-5p
;
hsa-mir-6765-5p
;
hsa-mir-1304-5p
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-mir-3188
;
hsa-mir-2467-5p
;
hsa-mir-3975
;
hsa-mir-5009-3p
;
hsa-mir-485-5p
;
hsa-mir-6884-5p
;
hsa-mir-4662a-5p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-138-1-3p
;
hsa-mir-4319
;
hsa-mir-125a-5p
;
hsa-mir-625-3p
;
hsa-mir-504-5p
;
hsa-mir-580-3p
;
hsa-mir-6867-3p
;
hsa-mir-6852-3p
;
hsa-mir-3909
;
hsa-mir-6770-5p
;
hsa-mir-1253
;
hsa-mir-7706
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-3162-3p
;
hsa-mir-3163
;
hsa-mir-4695-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-518e-3p
;
hsa-mir-2110
;
hsa-mir-6780b-5p
;
hsa-mir-4271
;
hsa-mir-4725-3p
;
hsa-mir-6888-5p
;
hsa-mir-570-5p
;
hsa-mir-548ba
;
hsa-mir-548ai
;
hsa-mir-548ag
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-5581-3p
;
hsa-mir-103a-2-5p
;
hsa-mir-6499-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-3158-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-136-5p
;
hsa-mir-6872-3p
;
hsa-mir-193a-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-6868-3p
;
hsa-mir-6749-3p
;
hsa-mir-3124-3p
;
hsa-mir-1248
;
hsa-mir-1237-3p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-5088-3p
;
hsa-mir-1260b
;
hsa-mir-1260a
;
hsa-mir-188-3p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-646
;
hsa-mir-1183
;
hsa-mir-1266-3p
;
hsa-mir-130a-3p
;
hsa-mir-130b-3p
;
hsa-mir-148a-3p
;
hsa-mir-148b-3p
;
hsa-mir-152-3p
;
hsa-mir-1825
;
hsa-mir-199a-5p
;
hsa-mir-199b-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-301a-3p
;
hsa-mir-301b-3p
;
hsa-mir-3666
;
hsa-mir-3671
;
hsa-mir-4295
;
hsa-mir-454-3p
;
hsa-mir-4762-5p
;
hsa-mir-607
Nearest miRNA
hsa-mir-1-1/Downstream/862821;
Nearest TSS
ENST00000382410/Upstream/21581;
ENST00000381941/Downstream/9930;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/67358
,
chr20-CpG: 30/Downstream/13481
Nearest cancer related gene
CSNK2A1
(OG, No orient, 0)
Upstream sequence
TAAAAattgagataaaatccatgtaacataaaactcatcattttagggtacaatcagtaccctaaaatggtgtgttttcgtatattcacaatgctgtgga
Downstream sequence
accatcaccactatctgattccagaacacttcatcgccccaaaaagaaacccagtacctcagaggattaactcccaatagcctcttcctacaatcctctg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL124
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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